In-Vitro Toxicology Market by Product & Services (Assay, Services and Reagents & Lab ware), Technology (Cell Culture, Cell Imaging, HTS and Toxic genomics), Method (Cellular Assays, Biochemical Assays, In-silicon, Ex-vivo), Application (Systemic Toxicology, Dermal Toxicity, Endocrine Disruption and Ocular Toxicity), End User - and Geography

In vitro toxicity testing studies the effects of toxic chemical substances on cultured cells or micro-tissues.  The development of 3D cell culture frameworks that mimic host physiology has empowered safe testing of new compunds in the in-vitro condition, in this way constraining the utilization of animal testing models. This has expanded the acknowledgment of in-vitro toxicology and computational strategies, thusly driving the market development. In-Vitro Toxicology is principally utilised to detect potentially hazardous chemicals in the early stages of development of new pharmaceuticals or agrichemicals. 

In-Vitro Toxicology Market Dynamics 

Variables that are driving in vitro toxicology market include the ethical concerns associated to the utilization of animal for pre-clinical examination, noteworthy progressions in-vitro toxicology assays, and increasing awareness concerning drug product safety. It is currently poised to take advantage of promising revolutions from the field of biotechnology. The applications of toxicity testing are set to increase with advances in biotechnology, resulting in a demand for the same in the market. The advances in toxicity testing practices, such as bioinformatics, computational toxicology, epigenetics, etc., hold the potential for a paradigm shift from whole-animal testing to in-vitro methods that evaluate changes in various processes, which use cell lines and other cellular components. These advances are expected to drive the growth of the in-vitro toxicology market over forecast period.

Besides, In-vitro toxicology assays enable rapid assessment of safety and offer cost-saving as well as time-saving advantages. Drug developers prefer in-vitro toxicology screening of their candidate drugs, further driving the adoption of these assays. 

In-Vitro Toxicology Market Segmental Highlights

The report analyses the global in-vitro toxicology market based on product, technology, method, application, end user and geography. 

• The various in vitro toxicology testing products incorporated in the study includes assays, services, and reagents. The various types of assays used to carry out in vitro toxicology consists bacterial toxicity assays, enzyme toxicity assays, cell-based ELISA and western blots, receptor-binding assays, tissue culture assays etc. 
• The assays segment observed to have large demand owing to the growing demand for high-quality reagents and the constant use of media and reagents in in-vitro toxicology studies. Whereas the services segment is likely to grow at the significant pace to the increasing trend of outsourcing of in vitro toxicity tests by small and medium-sized pharmaceutical and cosmetics companies. 
• In terms of technology, in vitro toxicology market is categorised into cell culture technologies, high-throughput technologies, cellular imaging technologies and toxic genomics. Cell culture technology hold the prominent share of the market as it serves as an excellent model for examining toxic effects since it provides consistent samples and reproducible results, which enables early-stage detection of toxicity in the drug development process. 
• By method, vitro toxicology market is bifurcated into cellular assays, biochemical assays, in-silico and ex vivo models.  The ex vivo models acts as an effective alternative to animal testing for the toxicity testing of cosmetics and household products, and growing  use of testing for cardio toxicity, hepatotoxicity, , nephrotoxicity, etc. Cellular assay dominated the market attributed to the broader availability of this technique for pharmacokinetic profiling of drug products. Besides, numerous pharmaceutical and biotechnological firms are largely dependent on cellular assays for toxicity screening in the early stages of drug development owing to various advantages offered by it including minimal cost, speed, and potential for automation. 
• The invitro toxicology finds application in systemic toxicology, dermal toxicity, endocrine disruption and occular toxicity. Dermal toxicity is anticipated to observe lucrative growth over the estimated timeframe. Toxicology assays for dermal toxicology have proven to be a simple, reliable, and cost-effective choice. Advancements concerning to the tools for dermal toxicity and risk assessment are likely to boost the segment growth. 
• The major end users of this market are pharmaceutical and biopharmaceutical industry, chemical industry, cosmetics and household products industry and food industry. 
• Based on geography, the global In-vitro toxicology market is studied for countries of key regions including North America, Europe, Asia Pacific and Rest of the World. North America accounted for the largest market share owing to the technological advancements and supportive government regulations.
• The Asia Pacific market is likely to register the highest CAGR over estimated timeframe. The rise of CROs for outsourcing toxicology-related research projects, growing pharmaceutical drug pipeline, and increasing consumer awareness of product safety are some of the key factors driving the growth of the in-vitro toxicology testing market in this region. 

Key players in the global In-Vitro Toxicology market include Bio-Rad Laboratories, Inc. Qiagen N.V. , GE Healthcare , Merck KGaA, Thermo Fisher Scientific, Inc , Charles River Laboratories International, Inc. , Catalent, Inc. , Agilent Technologies Inc, Eurofins Scientific, BioReliance, Inc., Alere, Inc., SGS S.A. , Covance, Inc., Promega Corporation  and Gentronix Limited among others.